Nurix Therapeutics Receives the US FDA’s IND Clearance for NX-1607 to Treat Advanced Malignancies
Shots:
- The company has received the US FDA’s clearance for the IND application to expand an ongoing P-I dose escalation and expansion trial to evaluate the safety and tolerability of NX-1607 in adults with advanced malignancies incl. a range of solid tumor indications
- Patients are now being enrolled in the trial in the UK with clinical sites in the US being added later. The result from initial biomarker data from the P-I trial are expected in H1’22
- NX-1607 is an orally bioavailable inhibitor of CBL-B for immuno-oncology indications incl. a range of solid tumor types. Additionally, the therapy showed single-agent anti-tumor activity in multiple tumor models
Ref: Nurix | Image: Nurix
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